This medication passes into breast milk, but is unlikely to harm a nursing infant. Consult your doctor before breast-feeding. Food and Drug Administration. WebMD does not endorse any specific product, service or treatment. Check the ingredients on the label even if you have used the product before. The manufacturer may have changed the ingredients. Also, products with similar names may contain different ingredients meant for different purposes. Taking the wrong product could harm you. NSAIDs such as celecoxib, ketorolac, or naproxen. These drugs are similar to ibuprofen and may increase your risk of side effects if taken together. However, if your doctor has directed you to take low-dose aspirin for heart attack or stroke prevention usually at dosages of 81-325 milligrams a day you should continue taking the aspirin unless your doctor instructs you otherwise.
As with any NSAIDs, caution should be exercised in treating the elderly 65 years and older. Carefully consider the potential benefits and risks of Ibuprofen Tablets, USP and other treatment options before deciding to use Ibuprofen Tablets, USP. Use the lowest effective dose for the shortest duration consistent with individual patient treatment goals see WARNINGS. When Should I Call the Doctor? Ibuprofen tablets cannot be expected to substitute for corticosteroids or to treat corticosteroid insufficiency. Abrupt discontinuation of corticosteroids may lead to disease exacerbation. Patients on prolonged corticosteroid therapy should have their therapy tapered slowly if a decision is made to discontinue corticosteroids.
For your information, the experts included physicians, nurses, pharmacologists, academics, industry, and patient advocates. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
The clinical significance of this interaction is not known; however, as with other NSAIDs, concomitant administration of ibuprofen and aspirin is not generally recommended because of the potential for increased adverse effects. Clinical studies, as well as post marketing observations, have shown that ibuprofen tablets can reduce the natriuretic effect of furosemide and thiazides in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis. During concomitant therapy with NSAIDs, the patient should be observed closely for signs of renal failure see WARNINGS, Renal Effects as well as to assure diuretic efficacy.
Have been treated for a vaginal, cervical, or pelvic infection. If you are receiving conscious sedation for your procedure, you may not eat or drink anything 8 hours before the procedure. This also includes your medication. If you have any questions about your medication, please ask your doctor or nurse and they will advise you about when you can take your medications. NSAIDs, including Ibuprofen Oral Suspension, can cause serious gastrointestinal GI adverse events including inflammation, bleeding, ulceration, and perforation of the stomach, small intestine, or large intestine, which can be fatal. These serious adverse events can occur at any time, with or without warning symptoms, in patients treated with NSAIDs. Only one in five patients, who develop a serious upper GI adverse event on NSAID therapy, is symptomatic. Upper GI ulcers, gross bleeding, or perforation caused by NSAIDs occur in approximately 1% of patients treated for 3-6 months, and in about 2-4% of patients treated for one year. These trends continue with longer duration of use, increasing the likelihood of developing a serious GI event at some time during the course of therapy. However, even short-term therapy is not without risk. This medication may make you more sensitive to the sun. Limit your time in the sun. Avoid tanning booths and sunlamps. Use and wear protective clothing when outdoors. The dosage is based on your medical condition and response to treatment. To reduce your risk of bleeding and other side effects, take this medication at the lowest effective dose for the shortest possible time. Do not increase your dose or take this drug more often than directed by your doctor or the package label. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs. Some products that may interact with this drug include: aliskiren, ACE inhibitors such as captopril, lisinopril angiotensin II receptor blockers such as losartan, valsartan cidofovir, corticosteroids such as prednisone lithium, "water pills" diuretics such as furosemide. After observing the response to initial therapy with ibuprofen tablets the dose and frequency should be adjusted to suit an individual patient's needs. It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk and because of the potential for serious adverse reactions in nursing infants from Motrin suspension, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. Because of the known effects of nonsteroidal anti-inflammatory drugs on the fetal cardiovascular system closure of ductus arteriosus use during pregnancy particularly late pregnancy should be avoided.
NSAIDs have been reported to competitively inhibit methotrexate accumulation in rabbit kidney slices. This may indicate that they could enhance the toxicity of methotrexate. Caution should be used when NSAIDs are administered concomitantly with methotrexate. Thankfully in 2011, the FDA Committees voted for standardized liquid dosing. If the fever is high or prolonged, it is wise to consult with a physician. Store at room temperature away from light and moisture. not store in the bathroom. Keep all away from children and pets. Look at the cervix for problem areas if an shows a high-risk type of HPV. Ibuprofen tablets contain ibuprofen which possesses analgesic and antipyretic activities. Its mode of action, like that of other NSAIDs, is not completely understood, but may be related to prostaglandin synthetase inhibition. This medicine may cause bleeding in your stomach or intestines. These problems can happen without warning signs. The dose of Ibuprofen Oral Suspension should be tailored to each patient, and may be lowered or raised from the suggested doses depending on the severity of symptoms either at time of initiating drug therapy or as the patient responds or fails to respond. If you would like more information about NSAIDs, talk with your healthcare provider. You can ask your pharmacist or healthcare provider for information about NSAIDs that is written for health professionals. In patients with primary dysmenorrhea, ibuprofen tablets have been shown to reduce elevated levels of prostaglandin activity in the menstrual fluid and to reduce resting and active intrauterine pressure, as well as the frequency of uterine contractions. The probable mechanism of action is to inhibit prostaglandin synthesis rather than simply to provide analgesia. Colposcopy and a cervical biopsy usually take about 15 minutes. gabapentin
NSAIDs have a greater than 10-fold risk for developing a GI bleed compared to patients with neither of these risk factors. Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. Most spontaneous reports of fatal GI events are in elderly or debilitated patients and therefore, special care should be taken in treating this population. Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Pagana KD, Pagana TJ 2010. This information should not be used to decide whether or not to take Motrin or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Motrin. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Motrin. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Motrin. The joint meeting of the FDA Advisory Committee for Nonprescription Drugs and the FDA Pediatric Advisory Committee took place on May 17th and 18th 2011. I wrote this article on May 18th. In March of 2015, someone on Facebook found this post and began to share it, even though the post had not been updated for four years. This took us by surprise, but pointed out the Tylenol for babies and toddlers is still an important topic to parents of young children. Ibuprofen Tablets, USP should be discontinued. Children under 4 should not be given medications containing dextromethorphan DXM. Children 4-11 can take DXM, but use caution and follow the directions carefully. Store at room temperature away from moisture and heat. Do not allow the liquid medicine to freeze. Site of action of narcotic and non-narcotic analgesics determined by blocking bradykinin-evoked visceral pain. Arch Intern Pharmacodyn. AU TGA pregnancy category C: Drugs which, owing to their pharmacological effects, have caused or may be suspected of causing, harmful effects on the human fetus or neonate without causing malformations. These effects may be reversible. Accompanying texts should be consulted for further details. The actual treatment time is about 15 minutes. It is important that you lie still during the treatment and do not move below your waist. You will be alone in the room during the treatment. Medical staff will be able to hear, see, and talk to you by way of an intercom system. You will be able to talk to them if you need anything. This medicine may raise your risk of having a heart attack or stroke. This is more likely in people who already have heart disease. Ibuprofen tablets, like other NSAIDs, can cause GI discomfort and, rarely, serious GI side effects, such as ulcers and bleeding, which may result in hospitalization and even death. Although serious GI tract ulcerations and bleeding can occur without warning symptoms, patients should be alert for the signs and symptoms of ulcerations and bleeding, and should ask for medical advice when observing any indicative signs or symptoms including epigastric pain, dyspepsia, melena, and hematemesis. Patients should be apprised of the importance of this follow-up see WARNINGS, Gastrointestinal Effects-Risk of Ulceration, Bleeding and Perforation. You are having a menstrual period at the time of the test. You should not use NSAIDs for pain if you are allergic to aspirin or similar drugs. Now you have a bunch of parents with their underwear in a twist over what to give for a fever instead of looking at the big issue with this article! ised.info travatan
American Osteopathic Association: "Sore Throat? For reduction of fever in patients aged 6 months up to 2 years of age. Even in what most call high fevers, this is the case. This effect has been attributed to inhibition of renal prostaglandin synthesis by ibuprofen. Thus, when ibuprofen and lithium are administered concurrently, subjects should be observed carefully for signs of lithium toxicity. Read circulars for lithium preparation before use of such concurrent therapy. Patients should promptly report signs and symptoms of unexplained weight gain or edema to their physicians. It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk and because of the potential for serious adverse reactions in nursing infants from ibuprofen tablets, a decision should be made whether to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother. Lab tests, including kidney function, complete blood cell counts, and blood pressure, may be done to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments. Several short-term controlled studies failed to show that Motrin tablets significantly affected prothrombin times or a variety of other clotting factors when administered to individuals on warfarin-type anticoagulants. However, because bleeding has been reported when Motrin tablets and other NSAIDs have been administered to patients on warfarin-type anticoagulants, the physician should be cautious when administering Motrin tablets to patients on anticoagulants. The effects of warfarin and NSAIDs on GI bleeding are synergistic, such that the users of both drugs together have a risk of serious GI bleeding higher than users of either drug alone. Borderline elevations of one or more liver tests may occur in up to 15% of patients taking NSAIDs, including ibuprofen tablets. These laboratory abnormalities may progress, may remain unchanged, or may be transient with continuing therapy. Notable elevations of ALT or AST approximately three or more times the upper limit of normal have been reported in approximately 1% of patients in clinical trials with NSAIDs. In addition, rare cases of severe hepatic reactions, including jaundice, fulminant hepatitis, liver necrosis, and hepatic failure, some of them with fatal outcomes have been reported. Primary Dysmenorrhea: For the treatment of primary dysmenorrhea, beginning with the earliest onset of such pain, Motrin Suspension should be given in a dose of 400 mg every 4 hours, as necessary, for the relief of pain. Janet P. Engle, Pharm. Motrin Suspension is contraindicated in patients with known hypersensitivity to ibuprofen. Some MEDICINES MAY INTERACT with Motrin. This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages. You should not take acetaminophen if you have three or more alcoholic drinks daily or if you have advanced liver disease. Thank you for validating what I have been practicing for my daughter for the past three years. Whenever my daughter gets a fever and not even very high my husband freaks out and want to give her acetaminophen to bring down her fever.
Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE-inhibitors. This interaction should be given consideration in patients taking NSAIDs concomitantly with ACE-inhibitors. Before having any kind of surgery or medical tests, tell your doctor that you are taking this medicine. WebMD User Reviews should not be considered as medical advice and are not a substitute for professional medical advice, diagnosis, or treatment. Never delay or disregard seeking professional medical advice from your physician or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences may be a helpful health information resource but they are never a substitute for professional medical advice from a qualified healthcare provider. Marfan syndrome, Sjogren's syndrome, or lupus. Ibuprofen is rapidly metabolized and eliminated in the urine. The excretion of ibuprofen is virtually complete 24 hours after the last dose. It looks like a pimple, and it can be sore. But it's not usually serious and won't affect how you see. In late pregnancy, as with other NSAIDs, ibuprofen should be avoided because it may cause premature closure of the ductus arteriosus. mestinon
Carefully follow the dosing instructions provided with children's ibuprofen for the age and weight of your child. Ask a doctor or pharmacist if you have questions. Heavy vaginal bleeding. This means more than a normal menstrual period. In studies with human volunteers, coadministration of cimetidine or ranitidine with ibuprofen had no substantive effect on ibuprofen serum concentrations. If you are taking this drug "as needed" not on a regular schedule remember that pain work best if they are used as the first occur. If you wait until the pain has worsened, the medication may not work as well. Motrin Suspension, like other NSAIDs, may cause serious CV side effects, such as MI or stroke, which may result in hospitalization, and even death. Although serious CV events can occur without warning symptoms, patients should be alert for the signs and symptoms of chest pain, shortness of breath, weakness, slurring of speech, and should ask for medical advice when observing any indicative sign or symptoms. Because serious GI tract ulcerations and bleeding can occur without warning symptoms, physicians should monitor for signs or symptoms of GI bleeding. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Tylenol, Ibuprofen, Motrin, Benadryl or any other OTC drugs. PDC and there were signs before ther vaccine at 18 months. Avoid taking NSAIDs after a recent heart attack, unless your healthcare provider tells you to. You may have an increased risk of another heart attack if you take NSAIDs after a recent heart attack. Ibuprofen tablets, like other NSAIDs, may cause serious CV side effects, such as MI or stroke, which may result in hospitalization and even death. Although serious CV events can occur without warning symptoms, patients should be alert for the signs and symptoms of chest pain, shortness of breath, weakness, slurring of speech, and should ask for medical advice when observing any indicative signs or symptoms. Patients should be apprised of the importance of this follow-up see WARNINGS, Cardiovascular Effects. Long-term administration of NSAIDs has resulted in renal papillary necrosis and other renal injury. Renal toxicity has also been seen in patients in whom renal prostaglandins have a compensatory role in the maintenance of renal perfusion. In these patients, administration of a nonsteroidal anti-inflammatory drug may cause a dose-dependent reduction in prostaglandin formation and, secondarily, in renal blood flow, which may precipitate overt renal decompensation. Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. Discontinuation of NSAID therapy is usually followed by recovery to the pretreatment state. Do not lie down for at least 10 minutes after taking this drug. If you have stomach upset while taking this medication, take it with food, milk, or an antacid. Ask your doctor or pharmacist about using this product safely. Parents, stop depending on big pharma to heal and cure your kids. Use your parental gut instincts when it comes to your kids and OTC meds and prescription drugs! brand glipizide cheap
Rest the muscle for at least a day. If these occur, patients should be instructed to seek immediate emergency help see WARNINGS. Lee WM. “Drug-Induced Hepatotoxicity. Please have someone come with you to your implant treatments, because you will not be able to drive yourself home. Not recommended during last trimester of pregnancy. Based on oral dosing data there is an age- or fever-related change in volume of distribution for ibuprofen. Reproductive studies conducted in rats and rabbits have not demonstrated evidence of developmental abnormalities. However, animal reproduction studies are not always predictive of human response. There are no adequate and well-controlled studies in pregnant women. Ibuprofen should be used in pregnancy only if the potential benefit justifies the potential risk to the fetus.
My boys are smart, well educated with good grades, are responsible, courteous, generous and HEALTHY! This is usually 8 to 12 days after the start of your last menstrual period. One fever study showed that, after the initial dose of Ibuprofen Oral Suspension, subsequent doses may be lowered and still provide adequate fever control. If an allergic reaction occurs, stop use and seek medical help right away. The other exception being when dehydration could be in play, as fever can speed that. Acetaminophen Tylenol along with a lukewarm bath may also help. Ibuprofen is a nonsteroidal anti-inflammatory drug NSAID that possesses anti-inflammatory, analgesic and antipyretic activity. Its mode of action, like that of other NSAIDs, is not completely understood, but may be related to prostaglandin synthetase inhibition. For certain conditions such as it may take up to two weeks of taking this drug regularly until you get the full benefit. Children's Motrin suspension comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Children's Motrin suspension refilled. where can i buy trazodone tablets
Ibuprofen may cause a severe allergic reaction, especially in people allergic to aspirin. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345. Two large, controlled clinical trials of a COX-2 selective NSAID for the treatment of pain in the first 10-14 days following CABG surgery found an increased incidence of myocardial infarction and stroke see CONTRAINDICATIONS. After hospitalization, parenteral hydration and three days bed rest, he recovered with no reported sequelae. Talk to your doctor about any concerns you have regarding the need for the test. Ask about its risks, how it will be done, or what the results will mean. To help you understand the importance of this test, fill out the What is a document? Studies in adults have established the dose-proportionality of ibuprofen as a single oral dose from 50 to 600 mg for total drug and up to 1200 mg for free drug. In patients taking Motrin or other NSAIDs, the most frequently reported adverse experiences occurring in approximately 1-10% of patients are: Abnormal renal function, anemia, dizziness, edema, elevated liver enzymes, fluid retention, gastrointestinal experiences including abdominal pain, bloating, constipation, diarrhea, dyspepsia, epigastric pain, flatulence, heartburn, nausea, vomiting headaches, increased bleeding time, nervousness, pruritus, rashes including maculopapular and tinnitus. Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your or local waste disposal company. Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Taking ibuprofen during the last 3 months of pregnancy may harm the unborn baby. Do not use ibuprofen and pseudoephedrine without a doctor's advice if you are pregnant. RxList is part of the WebMD Health Network. The opinions expressed in the WebMD User Reviews are solely those of the User, who may or may not have medical or scientific training, and do not represent the opinions of WebMD. These member reviews have not been reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other purpose except for compliance with our Terms and Conditions. You should not use this medicine if you are allergic to ibuprofen or pseudoephedrine, or if you have ever had an asthma attack or severe allergic reaction after taking aspirin or an NSAID. Drink plenty of fluids as directed by your doctor to prevent and tell your doctor right away if you have a change in the amount of urine. pharmacy champix brands
Since ibuprofen and pseudoephedrine is used when needed, you may not be on a dosing schedule. If you are on a schedule, use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose. What happens if I overdose? Borderline elevations of one or more liver tests may occur in up to 15% of patients taking NSAIDs including Ibuprofen Oral Suspension. These laboratory abnormalities may progress, may remain unchanged, or may be transient with continuing therapy. Notable elevations of ALT or AST approximately three or more times the upper limit of normal have been reported in approximately 1% of patients in clinical trials with NSAIDs. In addition, rare cases of severe hepatic reactions, including jaundice and fatal fulminant hepatitis, liver necrosis and hepatic failure, some of them with fatal outcomes have been reported. Ask a doctor or pharmacist before using any cold, allergy, or pain medicine. Many medicines available over the counter contain aspirin or other medicines similar to ibuprofen. Taking certain products together can cause you to get too much of this type of medication. Check the label to see if a medicine contains aspirin, ibuprofen, ketoprofen, or naproxen. Serum sickness, lupus erythe- matosus syndrome. In studies with human volunteers, co-administration of cimetidine or ranitidine with ibuprofen had no substantive effect on ibuprofen serum concentrations. Tylenol the first time bc of some reading i have done on the dangers of infant Tylenol. As with other NSAIDs, concomitant administration of IBUPROFEN and aspirin is not generally recommended because of the potential of increased adverse effects. The toxicity of ibuprofen overdose is dependent upon the amount of drug ingested and the time elapsed since ingestion, though individual response may vary, which makes it necessary to evaluate each case individually. Although uncommon, serious toxicity and death have been reported in the medical literature with ibuprofen overdosage. The most frequently reported symptoms of ibuprofen overdose include abdominal pain, nausea, vomiting, lethargy and drowsiness. Other central nervous system symptoms include headache, tinnitus, CNS depression and seizures. Metabolic acidosis, coma, acute renal failure and apnea primarily in very young children may rarely occur. Cardiovascular toxicity, including hypotension, bradycardia, tachycardia and atrial fibrillation, also have been reported. Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions. What happens if I miss a dose? Clinical trials of several COX-2 selective and nonselective NSAIDs of up to three years duration have shown an increased risk of serious cardiovascular CV thrombotic events, including myocardial infarction MI and stroke, which can be fatal. Based on available data, it is unclear that the risk for CV thrombotic events is similar for all NSAIDs. The relative increase in serious CV thrombotic events over baseline conferred by NSAID use appears to be similar in those with and without known CV disease or risk factors for CV disease. However, patients with known CV disease or risk factors had a higher absolute incidence of excess serious CV thrombotic events, due to their increased baseline rate. Some observational studies found that this increased risk of serious CV thrombotic events began as early as the first weeks of treatment. The increase in CV thrombotic risk has been observed most consistently at higher doses. NSAID medicines may increase the chance of a heart attack or stroke that can lead to death. This drug may make you dizzy or drowsy. not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit beverages. Ibuprofen tablets are contraindicated for treatment of peri-operative pain in the setting of coronary artery bypass graft CABG surgery see WARNINGS. This drug may rarely cause serious rarely fatal bleeding from the stomach or intestines. This effect can occur without warning at any time while taking this drug. Older adults may be at higher risk for this effect.
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This product contains a nonsteroidal anti-inflammatory drug NSAID which may cause stomach bleeding. Ibuprofen Oral Suspension should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. This will allow time for your cervix to heal. Do not for 1 day after your colposcopy. Taking ibuprofen during the last 3 months of pregnancy may harm the unborn baby. Do not use this medicine without a doctor's advice if you are pregnant. inderal cheap purchase online shopping
Ibuprofen tablets, like other NSAIDs, can cause serious skin side effects such as exfoliative dermatitis, SJS and TEN, which may result in hospitalization and even death. Although serious skin reactions may occur without warning, patients should be alert for the signs and symptoms of skin rash and blisters, fever, or other signs of hypersensitivity such as itching, and should ask for medical advice when observing any indicative signs or symptoms. Patients should be advised to stop the drug immediately if they develop any type of rash and contact their physicians as soon as possible. One person doing this is powerful and can answer the question for a particular child. With lots of us doing it we could learn so much so quickly!
Potter, Lisa Marie and Nicholas Weiler. “Short Sleepers Are Four Times More Likely to Catch a Cold. Elevate injured area above the person's level, if possible, for at least 24 hours. Use Motrin as directed by your doctor. Check the label on the medicine for exact dosing instructions. After observing the response to initial therapy with Motrin Suspension, the dose and frequency should be adjusted to suit an individual patient's needs. Fluid retention and edema have been observed in some patients taking NSAIDs. Motrin Suspension should be used with caution in patients with fluid retention or heart failure. donepezil
Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets. Aspirin is an NSAID but it does not increase the chance of a heart attack. Aspirin can cause bleeding in the brain, stomach, and intestines. Aspirin can also cause ulcers in the stomach and intestines. NSAID treatments should be carefully followed for signs and symptoms of early liver dysfunction.